- Solid state NMR structural biology of self-assembled peptides and proteins
- Self-assembly of the Alzheimer's beta-amyloid peptide
- Designer self-assembling peptides for applications in regenerative medicine
Professor Paravastu’s teaching interests include core chemical engineering principles at both undergraduate and graduate levels, with an emphasis on molecular-level understanding of biological and soft materials. His instruction integrates foundational courses in transport phenomena, thermodynamics, and biomolecular engineering, fostering a rigorous approach to the physical sciences underlying biochemical processes. He prioritizes active student engagement and the integration of interdisciplinary perspectives in his teaching.
B.S., 1998, Chemical Engineering, Massachusetts Institute of Technology
Ph.D., 2004, Chemical Engineering, University of California-Berkeley
Sajimon, M., Wheeler, C.J., Foley, A.R., Chan, K., Griffin, M.N., Dinakarapandian, D.M., Holberton, A., Joy, J., Paravastu, A.K., Wood, L.B., Raskatov, J.A. (2025) Asparagine Deamidation Attenuates Toxicity, Aggregation, and Microglial Responses of Alzheimer’s Amyloid-β. ACS Chemical Neuroscience, 16, 4076–4085.
Yao, Z.-F., Lim, S., Kuang, Y., Lundqvist, E.M., Celt, N., Chung, C.O., Lee, K.K., Nguyen, K., Le, L., Tang, S.W., Milligan, G.M., Kohl, P., Sudarshan, T.R., Li, Y., Eguchi, A., Paravastu, A.K., Zaragoza, M.V., Fishman, D.A., Ardoña, H.A.M. (2025) Complementary biomolecular coassemblies direct energy transport for cardiac photostimulators. Proceedings of the National Academy of Sciences of the United States of America, 122, e2509467122.
Rao Sudarshan, T., Lim, S., Li, J., Robang, A.S., Liberty, L.M., Ardona, H.A.M., Paravastu, A.K., (2024) Cooperative β-Sheet Coassembly Controls Intermolecular Orientation of Amphiphilic Peptide-Polydiacetylene Conjugates. Solid State Nuclear Magnetic Resonance, 133, 101959.
Robang, A.S., Roy, A., Dodd-o, J., He, D., Le, J., McShan, A.C., Hu, Y., Kumar, V., Paravastu, A.K. (2024), Structural consequences of introducing bioactive domains to designer β-sheet peptide self-assemblies. Biomacromolecules, 15, 1429.
Wong, K.M., Robang, A.S., Lint, A.H., Wang, Y., Dong, X., Xiao, X., Seroski, D.T., Liu, R., Shao, Q., Hudalla, G.A., Hall, C.K., Paravastu, A.K. (2021), Engineering β-sheet coassemblies for biomaterial applications. The Journal of Physical Chemistry B, 125, 13599.